Arch Foundation - Pathology
Support Fund - Oncology Project.  
Department head in Pathology - Dr. Keith Harris
Funds collected through Walk4Paws
will be used to directly support our tumor bank initiative, lead by
members of the Pathology Department and the Oncology Service of the
Teaching Hospital. Our vision is that, over time, material from the
tumor bank will be used to better understand the biology of different
forms of companion animal cancers leading to advances in diagnostics,
prognostics and treatments for a variety of tumor types.


*Recent and on-going cancer research conducted at the College of
Veterinary Medicine, University of Georgia*

1. Distribution of surviving in dog and cat tumors

2. Expression of heat shock proteins and Ki67 in canine brain tumors

3. Expression of histamine, serotonin, and c-kit in feline mast cell tumors

4. Use of indocyanin green and intraoperative spectroscopy and imaging
to determine tumor resection boundaries in dogs with soft tissue sarcomas

5. Canine prostate cancer as a model to study human hormone-resistant
prostate cancer

6. The role of COX inhibitors on the growth, invasion, and metastasis of
prostate cancer cells.

7. Use of proteomics to identify proteins differentially expressed
between normal and neoplastic canine prostate and bladder

8. Determination of miRNA expression profiles in canine lymphoma in
order to develop canine cancer-specific miRNA probes that can be used to
better diagnose, classify and predict outcomes in canine cancer patients.

9. Characterization of NF-kB expression in spontaneous SCC of domestic animals.

10. Streptozotocin chemotherapy for insulinoma in dogs.

11. Expression of 5-lipoxygenase expression in dogs with prostate carcinoma.

12. Immunohistochemical evaluation of heat shock proteins,
vasculoendothelial growth factor, and Ki-67 in canine brain tumors.

13. CCNU, vinblastine, and prednisone chemotherapy for dogs with
aggressive mast cell tumors.

14. MOPP rescue chemotherapy for dogs with resistant lymphoma.

15. Variation among pathologists in histologic grading of canine
cutaneous mast cell tumors.

16. Variation among pathologists in histologic grading of canine
cutaneous mast cell tumors with uniform use of a single grading reference.

17. Palliative radiation therapy for dogs with nasal tumors.

18. Development of a Canine tumor bank
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